如何使用Cochrane手册的MEDLINE检索式，能够举例说明，比如我想搜索儿童股骨颈骨折切开或闭合复位对股骨头坏死的发生率是否有影响，应当怎么修改检索式呢？

#1 randomized controlled trial [pt]

#2 controlled clinical trial [pt]

#3 randomized [tiab]

#4 placebo [tiab]

#5 drug therapy [sh]

#6 randomly [tiab]

#7 trial [tiab]

#8 groups [tiab]

#9 #1 OR #2 OR #3 OR #4 OR #5 OR #6 OR #7 OR #8

#10 animals [mh] NOT humans [mh]

#11 #9 NOT #10