Cox以及“独立”危险因素

老师好!我的论文是评价食管癌手术入路(左开胸 vs 右开胸)哪种效果好。有位审稿人提到“Co-variant factors should have been selected more meticulously to determine whether or not surgical approach had really been an “independent” prognosticator. The multivariate estimations were not sufficiently adjusted at all.”请问老师:他认为我的多因素分析没有得到充分调整,是指我纳入Cox模型中的协变量太少了对吗?说实话,确实是因为其他变量例数缺失比较多,我才没纳入。。。但我又不想承认是因为这个原因😂我应该如何回答他才好呢?ps:老师元宵节快乐!