Lancet:心脏瓣膜病:从机制到治疗

2024-04-02 来源:Lancet

本文由小咖机器人翻译整理

期刊来源:Lancet

原文链接:https://doi.org/10.1016/S0140-6736(23)02755-1

摘要内容如下:

瓣膜性心脏病是一种常见的疾病,其患病率在世界范围内迅速增加。有效的药物治疗是不够的,并且治疗在历史上仅限于瓣膜修复或置换的外科技术,导致对老年患者和患有严重合并症、虚弱或左心室功能不全的患者的系统性护理不足。在过去的20年里,影像学和外科技术的进步已经改变了心脏瓣膜病的治疗。对疾病机制和病因的更好理解,以及日益广泛和强大的证据基础,为多学科心脏团队在诊断设施和专业心脏瓣膜中心网络内提供个体化治疗提供了平台。在本系列文章中,我们旨在对瓣膜性心脏病的当前和未来管理进行概述,并基于对潜在病理生理学的理解和对个体患者多学科治疗策略的应用,提出治疗方法。

英文原文如下:

Abstracts

Valvular heart disease is common and its prevalence is rapidly increasing worldwide. Effective medical therapies are insufficient and treatment was historically limited to the surgical techniques of valve repair or replacement, resulting in systematic underprovision of care to older patients and those with substantial comorbidities, frailty, or left ventricular dysfunction. Advances in imaging and surgical techniques over the past 20 years have transformed the management of valvular heart disease. Better understanding of the mechanisms and causes of disease and an increasingly extensive and robust evidence base provide a platform for the delivery of individualised treatment by multidisciplinary heart teams working within networks of diagnostic facilities and specialist heart valve centres. In this Series paper, we aim to provide an overview of the current and future management of valvular heart disease and propose treatment approaches based on an understanding of the underlying pathophysiology and the application of multidisciplinary treatment strategies to individual patients.

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