本文由小咖机器人翻译整理

期刊来源：Ann Intern Med

原文链接：https://doi.org/10.7326/AITC202404160

摘要内容如下：

结直肠癌（CRC）是癌症死亡的第二大原因。筛查已被证明可以降低癌症发病率和癌症相关死亡率。有各种筛选测试，每一种都有自己的优点和缺点，并有不同程度的证据支持其使用。临床医生应为50至75岁的平均风险人群提供CRC筛查；从45岁开始筛查仍然存在争议。根据他们的总体健康状况和筛查史，对76至85岁的人进行筛查可能是有益的。为那些没有完成筛查的人提供筛查测试的选择或按顺序提供替代测试可以显著提高参与度。

英文原文如下：

Abstracts

Colorectal cancer (CRC) is the second leading cause of cancer death. Screening has been proven to reduce both cancer incidence and cancer-related mortality. Various screening tests are available, each with their own advantages and disadvantages and varying levels of evidence to support their use. Clinicians should offer CRC screening to average-risk persons aged 50 to 75 years; starting screening at age 45 years remains controversial. Screening may be beneficial in select persons aged 76 to 85 years, based on their overall health and screening history. Offering a choice of screening tests or sequentially offering an alternate test for those who do not complete screening can significantly increase participation.

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